Google's Android software in 3 out of 4 smartphones

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Read More..

How Computational Models Are Improving Medicine [Video]

























Click here to view the video


High-resolution electromechanical model of a heart; courtesy of N. Trayanova




















The more we learn about cancer, heart disease and Alzheimer’s, the more vexingly complex they seem–and the more elusive their cures. Even with cutting-edge imaging technology, biomarker tests and genetic data, we are still far from understanding the multifaceted causes and varied developmental stages of these illnesses. With the advent of powerful computing, better modeling programs and a flood of raw biomedical data, researchers have been anticipating a leap forward in their abilities to decipher the intricate dynamics involved human disease. Now, these computational capabilities are starting to arrive, according to a new analysis published online this week in Science Translational Medicine. In fact, “the field has exploded,” Raymond Winslow, director of the Johns Hopkins Institute for Computational Medicine, and co-author of the review, said in a prepared statement. Medicine and medical research largely have been focused on small specialties and narrow studies. But the body is a whole system–not isolated organ groups–and it is in constant interaction with the wider environment, including pollutants, toxins and other stressors. The resulting interactions do not only work in a single direction; instead, we have learned that there are feed-forward and feedback loops and crosstalk on cellular, molecular and genetic levels. This nexus is where advances in computational medicine are poised to make a large contribution. “Computational medicine can help you see how the pieces of the puzzle fit together to give a more holistic picture,” Winslow said. “We may never have all of the missing pieces, but will wind up with a much clearer view of what causes disease and how to treat it.” Models comparing gene expression in different patients have already successfully helped to determine different grades of prostate cancer, predict how different patients will respond to breast cancer treatment and find different types of stomach cancer. Scientists are also taking advantage of more advanced anatomical data to model whole organs and their function–and dysfunction. Using, for example, diffusion tensor magnetic resonance imaging, researchers can collect detailed information about heart anatomy, fiber and structure. This macro structure can be combined with more cellular-based models for “unprecedented structural and biophysical detail, including cardiac electromechanics,” the researchers noted in their paper. With this information, scientists are learning more about blood-flow dynamics, arrhythmia and heart attacks. These new models are now starting to be translated back to individual patients, to help find better treatments. Computational-medicine algorithms from detailed brain maps have already been used to develop an iPad app that is being used clinically to help doctors decide on deep brain stimulation locations and strengths. These models, however, also need to be checked frequently against real-world data and adjusted accordingly. But researchers who are armed to deal with this once unusual cross-discipline endeavor are growing more common. “There is a whole new community of people being trained in mathematics, computer science and engineering, and they are being cross-trained in biology,” Winslow said. “This allows them to bring a whole new perspective to medical diagnosis and treatment.” The myriad applications for computational medicine approaches are only beginning to be explored, the researchers noted. “As we gain confidence in the ability of computational models to predict human biological processes, they will help guide us through the complex landscape of disease, ultimately leading to more effective and reliable methods for disease diagnosis, risk stratification and therapy,” the researchers wrote. “We are poised at an exciting moment in medicine.”

Video of electromechanical heart model courtesy of N. Trayanova


Follow Scientific American on Twitter @SciAm and @SciamBlogs. Visit ScientificAmerican.com for the latest in science, health and technology news.
© 2012 ScientificAmerican.com. All rights reserved.


Health News Headlines – Yahoo! News



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AP PHOTOS: Stars come out for Sandy victims’ show

























NEW YORK (AP) — For the victims of Superstorm Sandy, it was a sorely needed message delivered.


From “Livin’ on a Prayer” to “The Living Proof,” every song Friday at NBC’s benefit concert became a message song.





















New Jersey‘s Jon Bon Jovi gave extra meaning to “Who Says You Can’t Go Home.” Billy Joel worked in a reference to Staten Island, the decimated New York City borough.


The hourlong event, hosted by Matt Lauer, was heavy on stars and lyrics identified with New Jersey and the New York metropolitan area, which took the brunt of this week’s deadly storm. The telethon was a mix of music, storm footage and calls for donations from Jon Stewart, Tina Fey, Whoopi Goldberg and others.


The show ended, as it only could, with Bruce Springsteen and the E Street Band, tearing into “Land Of Hope and Dreams.”


“God bless New York,” Springsteen, New Jersey‘s ageless native son, said in conclusion. “God bless the Jersey shore.”


Here, in pictures, are some of the performers on this somber but hopeful night:


Entertainment News Headlines – Yahoo! News



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Syria army quits base on strategic Aleppo road

























BEIRUT (Reuters) – The Syrian army abandoned its last base near the northern town of Saraqeb after a fierce assault by rebels, further isolating the strategically important second city Aleppo from the capital.


But in a political setback to forces battling to topple President Bashar al-Assad, the United Nations said the rebels appeared to have committed a war crime after seizing the base.





















The opposition Syrian Observatory for Human Rights said on Friday government troops had retreated from a post northwest of Saraqeb, leaving the town and surrounding areas “completely outside the control of regime forces”.


It was not immediately possible to verify the reported army withdrawal. Authorities restrict journalists’ access in Syria and state media made no reference to Saraqeb.


The pullout followed coordinated rebel attacks on Thursday against three military posts around Saraqeb, 50 km (30 miles) southwest of Aleppo, in which 28 soldiers were killed.


Several were shown in video footage being shot after they had surrendered.


“The allegations are that these were soldiers who were no longer combatants. And therefore, at this point it looks very likely that this is a war crime, another one,” U.N. human rights spokesman Rupert Colville said in Geneva.


“Unfortunately this could be just the latest in a string of documented summary executions by opposition factions as well as by government forces and groups affiliated with them, such as the shabbiha (pro-government militia),” he said.


Video footage of the killings showed rebels berating the captured men, calling them “Assad’s dogs”, before firing round after round into their bodies as they lay on the ground.


Rights groups and the United Nations say rebels and forces loyal to President Bashar al-Assad have committed war crimes during the 19-month-old conflict. It began with protests against Assad and has spiraled into a civil war which has killed 32,000 people and threatens to drag in regional powers.


The mainly Sunni Muslim rebels are supported by Sunni states including Saudi Arabia, Qatar and neighboring Turkey. Shi’ite Iran remains the strongest regional supporter of Assad, who is from the Alawite faith which is an offshoot of Shi’ite Islam.


STRATEGIC BLOW


Saraqeb lies at the meeting point of Syria’s main north-south highway, linking Aleppo with Damascus, and another road connecting Aleppo to the Mediterranean port of Latakia.


With areas of rural Aleppo and border crossings to Turkey already under rebel control, the loss of Saraqeb would leave Aleppo city further cut off from Assad’s Damascus powerbase.


Any convoys using the highways from Damascus or the Mediterranean city of Latakia would be vulnerable to rebel attack. This would force the army to use smaller rural roads or send supplies on a dangerous route from Al-Raqqa in the east, according to the Observatory’s director, Rami Abdelrahman.


In response to the rebels’ territorial gains, Assad has stepped up air strikes against opposition strongholds, launching some of the heaviest raids so far against working class suburbs east of Damascus over the last week.


The bloodshed has continued unabated despite an attempted ceasefire, proposed by join U.N.-Arab League envoy Lakhdar Brahimi to mark last month’s Muslim holiday of Eid al-Adha.


In the latest in a string of fruitless international initiatives, China called on Thursday for a phased, region-by-region ceasefire and the setting up of a transitional governing body – an idea which opposition leaders hope to flesh out at a meeting in Qatar next week.


Veteran opposition leader Riad Seif has proposed a structure bringing together the rebel Free Syrian Army, regional military councils and other rebel forces alongside local civilian bodies and prominent opposition figures.


His plan, called the Syrian National Initiative, calls for four bodies to be established: the Initiative Body, including political groups, local councils, national figures and rebel forces; a Supreme Military Council; a Judicial Committee and a transitional government made up of technocrats.


The initiative has the support of Washington. U.S. Secretary of State Hillary Clinton called on Wednesday for an overhaul of the opposition, saying it was time to move beyond the troubled Syrian National Council.


The SNC has failed to win recognition as the legitimate representative of the Syrian people and Clinton said it was time to bring in “those on the front lines fighting and dying”.


(Additional reporting by Oliver Holmes in Beirut and Stephanie Nebehay in Geneva; Editing by Jon Boyle)


World News Headlines – Yahoo! News



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With three days to go, Romney calls his campaign a ‘movement’

Republican presidential candidate Mitt Romney (Jim Young/Reuters)PORTSMOUTH, N.H.—Mitt Romney kicked off a whirlwind weekend of campaigning across the country in the state where he launched his bid for the presidency, expressing confidence that he will win the election.


"New Hampshire won me the Republican nomination, and New Hampshire is going to get me to the White House," the Republican nominee said at the first of four scheduled rallies on Saturday.


Speaking to more than 1,000 voters here at a chilly airport rally, Romney sounded a more retrospective note heading into the final weekend of the campaign.


"I've watched over the last few months as our campaign has gone from a start to a movement. It's not just the size of the crowds. It's the conviction and compassion in the hearts of the people," Romney said. "It's made me strive to be more worthy of the support I have received across the country and to campaign as I would govern, to speak for the aspirations of all Americans, not just some Americans."


From here, Romney will travel to Dubuque, Iowa, and then to Colorado, where he will hold rallies in Colorado Springs and Englewood. He'll spend the night in Des Moines, where he's scheduled to hold a rally Sunday morning.


Saturday's rally was Romney's first appearance in this hotly contested swing state in more than a month. Romney launched his campaign in the state in June 2011 and will hold his final rally here on Monday night in Manchester. Recent polls have found the GOP nominee statistically tied with President Barack Obama heading into Election Day.


Read More..

Google's Android software in 3 out of 4 smartphones

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Sister company to meningitis-linked firm extends shutdown

























(Reuters) – Ameridose LLC, sister company to the pharmacy at the heart of the U.S. meningitis outbreak, will extend its shutdown by an additional two weeks, under an agreement between the company and Massachusetts regulators.


Friday’s accord comes two days after Ameridose issued a voluntary recall of all its products following a U.S. Food and Drug Administration directive to improve its sterility testing process.





















The Westborough, Massachusetts-based company, which was closed on October 10, said on Wednesday it had not received any reports of adverse reactions to the drugs it is recalling.


Ameridose is owned by the same people who own the New England Compounding Center, which distributed a tainted steroid that has killed 28 people.


(Reporting By Toni Clarke; Editing by Gerald E. McCormick)


Medications/Drugs News Headlines – Yahoo! News



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Suicide Silence singer Lucker dies in California motorcycle accident

























LOS ANGELES (Reuters) – Mitch Lucker, the lead singer of extreme heavy metal band Suicide Silence, died on Thursday of injuries suffered in a motorcycle accident in Huntington Beach, California, police said.


The band from Southern California was given the Golden Gods award for best new talent by Revolver magazine in 2009.





















Lucker, 28, was on a new Harley Davidson motorcycle driving in the Orange County city of Huntington Beach on Halloween night when he lost control and crashed into a light pole, according to a statement from the local police department.


He was taken to the University of California, Irvine Medical Center where he later died, police said. Investigators said they were looking into the cause of the collision and whether alcohol was a factor.


“There’s no easy way to say this,” the band said in a post on Facebook. “Mitch passed away earlier this morning from injuries sustained during a motorcycle accident.”


Suicide Silence in 2007 came out with the album “The Cleansing” and followed that up with the 2009 “No Time to Bleed” and last year’s “The Black Crown,” which made its way to No. 9 on the Billboard hard rock chart.


The band, whose musical style is referred to as “deathcore,” is originally from Riverside, California, a working-class community 50 miles east of Los Angeles.


(Reporting by Alex Dobuzinskis; Editing by Cynthia Johnston and Will Dunham)


Music News Headlines – Yahoo! News



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Syrian rebels kill 28 soldiers, several executed

























BEIRUT (Reuters) – Anti-government rebels killed 28 soldiers on Thursday in attacks on three army checkpoints around Saraqeb, a town on Syria’s main north-south highway, a monitoring group said.


Some of the dead were shot after they had surrendered, according to video footage. Rebels berated them, calling them “Assad’s Dogs”, before firing round after round into their bodies as they lay on the ground.





















The highway linking the capital Damascus to the contested city of Aleppo, Syria’s commercial center, has been the scene of heavy fighting since rebels cut the road last month. Saraqeb lies about 40 km (25 miles) south of Aleppo


In other developments, China put forward a new initiative to resolve the 19-month-old conflict, including a phased, region-by-region ceasefire and the setting up of a transitional governing body.


A Chinese Foreign Ministry spokesman said Beijing had made the proposal to international peace envoy Lakhdar Brahimi – whose own call for a truce over the Muslim holiday of Eid was largely ignored by both sides.


The United States meanwhile has called for an overhaul of Syria’s opposition leadership, signaling a break with the largely foreign-based Syrian National Council to bring in more credible figures.


A meeting in Qatar next week of foreign powers backing the rebels will be an opportunity to broaden the coalition against President Bashar al-Assad, U.S. Secretary of State Hillary Clinton said in Zagreb on Wednesday.


The United States and its allies have struggled for months to craft a credible opposition coalition, while Assad has counted on the support of Russia, Iran and, to a lesser extent, China. International efforts to end the violence have all foundered.


More than 32,000 people have been killed since protests against Assad, an Alawite who succeeded his late father Hafez in ruling the mostly Sunni Muslim country, first broke out on city streets. The revolt has since degenerated into full-scale civil war, with the government forces relying heavily on artillery and air strikes to thwart the rebels.


CHECKPOINT ATTACKS


The army has lost swathes of land in Idlib and Aleppo provinces but is fighting to control towns along supply routes to Aleppo city, where its forces are fighting in many districts.


The head of the pro-opposition Syrian Observatory for Human Rights, Rami Abdelrahman, said two of the attacked checkpoints at Saraqeb were on the Damascus-Aleppo highway. The third was near a road linking Aleppo with Latakia, a port city still mostly controlled Assad’s forces.


“The rebels will not stay at the checkpoints for long as Syrian warplanes normally bomb positions after rebels move in,” Abdelrahman said.


Five rebels died in the fighting and at least 20 soldiers were killed at the third site, including those shot after surrendering, he said.


The video footage showed a group of petrified men, some bleeding, lying on the ground as rebels walked around, kicking and stamping on their captives.


One of the captured men says: “I swear I didn’t shoot anyone” to which a rebel responds: “Shut up you animal … Gather them for me.” Then the men are shot dead.


Reuters could not independently verify the footage.


The Observatory said the al Qaeda-inspired Jabhat al-Nusra rebel group was responsible for the executions.


Islamist rebel units are growing in prominence in the war – a cause for concern for international powers as they weigh up what kind of support to give the opposition.


U.S. President Barack Obama’s administration has said it is not providing arms to internal opponents of Assad and is limiting its aid to non-lethal humanitarian assistance. It concedes, however, that some of its allies are providing lethal assistance.


Russia and China have blocked three U.N. Security Council resolutions aimed at increasing pressure on the Assad government, leading the United States and its allies to say they could move beyond U.N. structures for their next steps.


China has been strongly criticized by some Arab countries for failing to take a stronger stance on the conflict. Beijing has urged the Assad government to talk to the opposition and take steps to meet demands for political change.


“More and more countries have come to realize that a military option offers no way out, and a political settlement has become an increasingly shared aspiration,” Chinese Foreign Ministry spokesman Hong Lei said in Beijing.


He said China’s new proposal was aimed at building international consensus and supporting peace envoy Brahimi’s mediation efforts.


(Additional reporting by Ayat Basma, Laila Bassam and Dominic Evans in Beirut and Terril Yue Jones in Beijing; Writing by Oliver Holmes; Editing by Angus MacSwan)


World News Headlines – Yahoo! News



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Will final jobs report affect the election?

President Barack Obama and Republican rival Mitt Romney on Friday seized on the last jobs report before Election Day to reinforce their political arguments about the economy. Neither side, however, expected that the better-than-expected news would change many minds.


In a statement, Romney said that come Tuesday the choice would be "between stagnation and prosperity."


Obama, meanwhile, in front of a rowdy crowd of cheering supporters at the Franklin County Fairgrounds in Hilliard, Ohio, said, "This morning we learned that companies hired more workers in October than at any time in the last eight months.


"We've made real progress--but we are here today because we know we've got more work to do," Obama continued. "As long as there's a single American who wants a job and can't find one, as long as there are families working harder but falling behind, as long as there's a child anywhere in this country who's languishing in poverty and barred from opportunity, our fight goes on, we've got more work to do."


Neither campaign expected the new figure to do much to change the dynamic of the race. Aides on both sides have said in recent weeks that Americans' views of the economy are essentially fixed by now, barring a dramatic change.


The Labor Department's monthly jobs report did not provide such a tectonic shift. It showed that the economy added more jobs than experts had predicted and bolstered Obama's argument that he has overseen a slow but steady recovery from the 2007-2008 global economic meltdown.


At the same time, Republicans led by Romney seized on the news to charge that the incumbent has failed to bring about sturdier growth. At the current rate, it would take years to return to pre-recession levels. And no incumbent has faced the voters with unemployment this high since Franklin D. Roosevelt.


"On Tuesday, America will make a choice between stagnation and prosperity," Romney also said. "For four years, President Obama has told us that things are getting better and that we're making progress. For too many American families, those words ring hollow. We can do better."


Non-farm payrolls added 171,000 jobs last month, beating forecasts of about 125,000. The Labor Department also revised its previous estimates of employment growth in August and September upward by 84,000 jobs.


The unemployment rate ticked up from 7.8 percent to 7.9 percent, but chiefly as a result of more Americans getting off the sidelines and looking for work (those not looking are not counted in the jobless rate). Democrats emphasized that Obama had inherited a disastrous economy from George W. Bush and reversed what had been accelerating jobs losses. Republicans noted that the unemployment rate when Obama took office was 7.8 percent.


"Today's increase in the unemployment rate is a sad reminder that the economy is at a virtual standstill," Romney added. "The jobless rate is higher than it was when President Obama took office, and there are still 23 million Americans struggling for work."


One of the political challenges for Romney was that unemployment was lower than the national average in some critical battleground states. In September, it was 7 percent in Ohio, and 5.9 percent in Virginia.


An ABC News/Washington Post poll released on Thursday painted a mixed picture of voters' views about the economy. Fifty-four percent of likely voters expressed confidence that the economy would improve under Romney, against 47 percent for Obama. But 51 percent of those surveyed still blamed George W. Bush for the current conditions, against 36 percent for Obama. The Democrat has made tying Romney to Bush a centerpiece of his closing argument.


Read More..